Environmental trends pose escalating threats to public health globally. This presentation examines key environmental changes, their wide-ranging health impacts, and the disproportionate effects on vulnerable populations through the social determinants of health in the United States. It concludes by exploring comprehensive prevention strategies, empowering healthcare professionals and the public to address these critical challenges effectively.To learn more about the President's Lecture Series and to view upcoming presentation topics, visit regisma.me/49DNH39